Clinical Effects of Ozone Therapy

I found this information on the clinical effects of ozone at


Ozone can produce different effects according to the chosen concentration and the way of its administration. There are plenty of studies that back up the following comments.
Bactericidal, fungicidal and virucidal
Therapeutic ozone indirectly activates the non-specific defense system as well as components of cellular and humoral immunity.
Oxidizes the compounds containing double bonds which participate in the development and sustaining of the inflammatory process, regulates metabolic reactions and resolves pH.
Ozone analgesic effect
Oxidates the products that act on the nerve endings in damaged tissue and determines the intensity of pain response.
Correction and activation of metabolic processes in the hepatic and renal tissues.
Activation of oxygen-dependent processes
The increase in the content of free and dissolved blood oxygen plus mitochondrial activation results in ATP synthesis.
Optimization of pro- and anti-oxidant
The influence on cellular membranes and balancing of the levels of lipid peroxidation products.
Haemostatic effect
High concentrations with external use cause a hyper coagulation effect, while parenteral administration of low concentrations is characterized by a decrease in thrombocytic and coagulative values.
Immunomodulating effect
Patients with auto-immune pathology (rheumatoid arthritis, muscular sclerosis, vitiligo, lupus, etc.) can benefit from adjusting the immune response


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